Marilena Koutsami PULMONOLOGIST

«Centrosome abnormalities in non-small-cell lung cancer and their association with cyclin E overexpression». Laboratory of Histology-Embryology, Molecular Carcinogenesis Group, Medical School, National and Kapodistrian University of Athens, 2003-2006

European Respiratory Society 

• Consultant of Hygeia Hospital, Athens, Greece (February 2014- present)
• Private Practice (February 2013- present)
• Associate researcher of Molecular Carcinogenesis Group, Histology- Embryology Laboratory, Medical School of Athens University.

Clinical Interest:
  • Thoracic Oncology, COPD, Asthma, Interstitial Lung Diseases

Research Interest: 

• Molecular carcinogenesis
• Participation in research programmes

Award “Prof. Papaharalampous” for “ Study of centrosomal abnormalities in NSCLCs and their correlation with aneuploidy and cyclin E overexpression”. 10nth Pathology Congress, Ioannina, May 2006

1. “The mos proto-oncogene, a meiotic gene in cancer development”, Chapter 2, Volume 2: 16-33, Genes, Genomes and Genomics.

2. E-class lessons for “Respiratory system” and “Muscular system”, Laboratory of Histology-Embryology, 2005

1. Eleftherios Zervas, Konstantinos Samitas , Stelios Vittorakis, MARILENA KOUTSAMI, Athanasios Thomopoulos, Adamantia Liapikou, Erasmia Economidou, Mina Gaga. Safety of research bronchoscopy in mild-moderate and severe asthma. Pneumon 2010, 23(1):41-47.

2. MARILENA KOUTSAMI, Georgia Velimezi, Athanassios Kotsinas, Konstantinos Evangelou, Athanassios G Papavassiliou, Christos Kittas, and Vassilis G. Gorgoulis. Is exclusive Skp2 targeting always beneficial in cancer therapy? Blood, 1 December 2008, Vol. 112, No. 12, pp. 4777-4779.

3. Liontos M*, KOUTSAMI M*, Sideridou M*, Evangelou K, Kletsas D, Levy B, Kotsinas A, Nahum O, Zoumpourlis V, Kouloukoussa M, Lygerou Z, Taraviras S, Kittas C, Bartkova J, Papavassiliou AG, Bartek J, Halazonetis TD, Gorgoulis VG.Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior. Cancer Res. 2007 Nov 15;67(22):10899-909.

4. Pateras SI, Apostolopoulou K, KOYTSAMI M, Evangelou L, Tsantoulis P, Liloglou T, Nikolaidis G, Sigala F, Kittas C, Kotsinas A, Gorgoulis V: Inhibition of the SKP2-degradation pathway along with CDKN1C promoter demethylation restores p57KIP2 levels in non-small cell lung cancer. Int J Cancer. 2006 Dec 1; 119(11):2546-56.

5. KOUTSAMI ΜΚ, Tsantoulis PK, Kouloukoussa M, Apostolopoulou K, Pateras IS, Spartinou Z, Drougou A, Evangelou K, Kittas C, Bartkova J, Bartek J, G Gorgoulis V: Centrosomal abnormalities are frequently observed in non-small-cell lung cancer and are associated with aneuploidy and Cyclin E overexpression. J Pathol 2006, Volume 209, 4: 512-521,

6. KOUTSAMI MK, Doussis-Anagnostopoulou I, Papavassiliou AG, Gorgoulis VG. Genetic and molecular coordinates of neuroendocrine lung tumors, with emphasis on small-cell lung carcinomas. Mol Med 2002 Aug;8(8):419-36.

7. KOUTSAMI MK, Gorgoulis VG, Kastrinakis NG, Asimacopoulos PJ, Kittas C: Prognostic factors in non-small cell lung carcinoma. Anticancer Res 2002 Jan-Feb; 22 (1A):347-74.